Publikationen von H. Wekerle
Alle Typen
Zeitschriftenartikel (103)
2010
Zeitschriftenartikel
Zero Tolerance (to Acetylcholine Receptor) and Ways to Overcome It. Annals of Neurology 67 (4), S. 422 - 424 (2010)
Zeitschriftenartikel
Fragile privileges: Autoimmunity in brain and eye. Acta Pharmacologica Sinica 31 (9), S. 1141 - 1148 (2010)
2009
Zeitschriftenartikel
Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions. Nature 462 (7269), S. 94 - 98 (2009)
Zeitschriftenartikel
β1 integrins differentially control extravasation of inflammatory cell subsets into the CNS during autoimmunity. Proceedings of the National Academy of Sciences of the United States of America 106 (6), S. 1920 - 1925 (2009)
Zeitschriftenartikel
Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals. Proceedings of the National Academy of Sciences of the United States of America 106 (20), S. 8302 - 8307 (2009)
Zeitschriftenartikel
MicroRNA profiling of multiple sclerosis lesions identifies modulators of the regulatory protein CD47. Brain 132, S. 3342 - 3352 (2009)
Zeitschriftenartikel
Myelin-specific T cells also recognize neuronal autoantigen in a transgenic mouse model of multiple sclerosis. Nature Medicine 15 (6), S. 626 - 632 (2009)
Zeitschriftenartikel
EAE: An immunologist's magic eye. European Journal of Immunology 39 (8), S. 2031 - 2035 (2009)
Zeitschriftenartikel
Spontaneous relapsing-remitting EAE in the SJL/J mouse: MOG-reactive transgenic T cells recruit endogenous MOG-specific B cells. Journal of Experimental Medicine 206 (6), S. 1303 - 1316 (2009)
2008
Zeitschriftenartikel
Reflections on the "intrathymic pathogenesis" of myasthenia gravis. Journal of Neuroimmunology 201-202, S. 21 - 27 (2008)
Zeitschriftenartikel
Matching of oligoclonal immunoglobulin transcriptomes and proteomes of cerebrospinal fluid in multiple sclerosis. Nature Medicine 14 (6), S. 688 - 693 (2008)
2007
Zeitschriftenartikel
Transition from enhanced T cell infiltration to inflammation in the myelin-degenerative central nervous system. Neurobiology of Disease 28 (3), S. 261 - 275 (2007)
Zeitschriftenartikel
Multiple sclerosis: T-cell receptor expression in distinct brain regions. Brain 130, S. 2789 - 2799 (2007)
Zeitschriftenartikel
Experimental models of spontaneous in the central nervous system. Journal of Molecular Medicine-JMM 85 (11), S. 1161 - 1173 (2007)
Zeitschriftenartikel
Blood-borne soluble protein antigen intensifies T cell activation in autoimmune CNS lesions and exacerbates clinical disease. Proceedings of the National Academy of Sciences of the United States of America 104 (47), S. 18625 - 18630 (2007)
Zeitschriftenartikel
Instant effect of soluble antigen on effector T cells in peripheral immune organs during immunotherapy of autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America 104 (3), S. 920 - 925 (2007)
Zeitschriftenartikel
L'énigme de l'entrée des lymphocytes T auto-immuns dans les tissus nerveux centraux et de leur attaque contre les structures de myéline. Comptes Rendus Biologies 330 (1), S. 1 - 12 (2007)
2006
Zeitschriftenartikel
The neuroprotective effect of inflammation: Implications for the therapy of multiple sclerosis. Neurological Sciences 27, S. S1 - S7 (2006)
Zeitschriftenartikel
Spontaneous opticospinal encephalomyelitis in a double-transgenic mouse model of autoimmune T cell B cell cooperation. The Journal of Clinical Investigation 116 (9), S. 2385 - 2392 (2006)
Zeitschriftenartikel
Reconstitution of paired T cell receptor α- and β-chains from microdissected single cells of human inflammatory tissues. Proceedings of the National Academy of Sciences of the United States of America 103 (32), S. 12057 - 12062 (2006)
Zeitschriftenartikel
Animal models of multiple sclerosis. Drug Discovery Today: Disease Models 3 (4), S. 359 - 367 (2006)
Zeitschriftenartikel
Organ specific autoantigens and the autoreactive T cell repertoire: The case of myelin oligodendrocyte glycoprotein. European Journal of Immunology 36 (3), S. 512 - 515 (2006)
2005
Zeitschriftenartikel
Complementary contribution of CD4 and CD8 T lymphocytes to T-cell infiltration of the intact and the degenerative spinal cord. American Journal of Pathology 166 (5), S. 1441 - 1450 (2005)
Zeitschriftenartikel
Glatiramer acetate in multiple sclerosis: Update on potential mechanisms of action. Lancet Neurology 4 (9), S. 567 - 575 (2005)
Zeitschriftenartikel
Drug insight: Using monoclonal antibodies to treat multiple sclerosis. Nature Clinical Practice Neurology 1, S. 34 - 44 (2005)
Zeitschriftenartikel
Live imaging of effector cell trafficking and autoantigen recognition within the unfolding autoimmune encephalomyelitis lesion. Journal of Experimental Medicine 201 (11), S. 1805 - 1814 (2005)
Zeitschriftenartikel
Autoimmune CD4(+) T cell memory: Lifelong persistence of encephalitogenic T cell clones in healthy immune repertoires. Journal of Immunology 175 (1), S. 69 - 81 (2005)
Zeitschriftenartikel
BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma. Journal of Experimental Medicine 201 (2), S. 195 - 200 (2005)
Zeitschriftenartikel
Immune pathogenesis of multiple sclerosis. Neurological Sciences 26 (1), S. S1 - S2 (2005)
Zeitschriftenartikel
Planting and pruning in the brain: MHC antigens involved in synaptic plasticity? Proceedings of the National Academy of Sciences of the United States of America 102 (1), S. 3 - 4 (2005)
2004
Zeitschriftenartikel
Selective and antigen-dependent effects of myelin degeneration on central nervous system inflammation. Journal of Neuropathology and Experimental Neurology 63 (12), S. 1284 - 1296 (2004)
Zeitschriftenartikel
Autoimmune concepts of multiple sclerosis as a basis for selective immunotherapy: From pipe dreams to (therapeutic) pipelines. Proceedings of the National Academy of Sciences of the United States of America 101 (Suppl. Suppl. 2), S. 14599 - 14606 (2004)
Zeitschriftenartikel
The activation status of neuroantigen-specific T cells in the target organ determines the clinical outcome of autoimmune encephalomyelitis. Journal of Experimental Medicine 199 (2), S. 185 - 197 (2004)
Zeitschriftenartikel
Live-imaging of encephalitogenic T lymphocytes in the living target tissue. Journal of Neuroimmunology 154 (1-2 Sp. Iss. Sp. Iss. SI), S. 224 - 224 (2004)
Zeitschriftenartikel
Multiple sclerosis: Brain-infiltrating CD8(+) T cells persist as clonal expansions in the cerebrospinal fluid and blood. Proceedings of the National Academy of Sciences of the United States of America 101 (8), S. 2428 - 2433 (2004)
2003
Zeitschriftenartikel
T-cell-mediated autoimmunity - Novel techniques to characterize autoreactive T-cell receptors. American Journal of Pathology 163 (4), S. 1215 - 1226 (2003)
Zeitschriftenartikel
Clonal tracking of autoaggressive T cells in polymyositis by combining laser microdissection, single-cell PCR, and CDR3-spectratype analysis. Proceedings of the National Academy of Sciences of the United States of America 100 (7), S. 4090 - 4095 (2003)
Zeitschriftenartikel
Neurotrophic cross-talk between the nervous and immune systems: Implications for neurological diseases. Annals of Neurology 53 (3), S. 292 - 304 (2003)
Zeitschriftenartikel
Molecular mimicry in multiple sclerosis. New England Journal of Medicine 349 (2), S. 185 - 186 (2003)
2002
Zeitschriftenartikel
Endoplasmic reticulum stress in PLP-overexpressing transgenic rats: Gray matter oligodendrocytes are more vulnerable than white matter oligodendrocytes. Journal of Neuropathology and Experimental Neurology 61 (1), S. 12 - 22 (2002)
Zeitschriftenartikel
Tumor necrosis factor inhibits neurite outgrowth and branching of hippocampal neurons by a Rho-dependent mechanism. The Journal of Neuroscience 22 (3), S. 854 - 862 (2002)
Zeitschriftenartikel
Immune protection of the brain - Efficient and delicate. The Journal of Infectious Diseases 186 (Suppl. 2), S. S140 - S144 (2002)
Zeitschriftenartikel
Tackling multiple sclerosis. Nature 420 (6911), S. 39 - 40 (2002)
Zeitschriftenartikel
An autoreactive gamma delta TCR derived from a polymyositis lesion. Journal of Immunology 169 (1), S. 515 - 521 (2002)
2001
Zeitschriftenartikel
Anti-inflammatory activity of nerve growth factor in experimental autoimmune encephalomyelitis: Inhibition of monocyte transendothelial migration. European Journal of Immunology 31 (1), S. 11 - 22 (2001)
Zeitschriftenartikel
Transection of major histocompatibility complex class I-induced neurites by cytotoxic T lymphocytes. American Journal of Pathology 159 (3), S. 809 - 815 (2001)
2000
Zeitschriftenartikel
The neuroprotective effect of inflammation: Implications for the therapy of multiple sclerosis. Journal of Neuroimmunology 107 (2), S. 161 - 166 (2000)
1999
Zeitschriftenartikel
Transgenic Lewis rats overexpressing the proteolipid protein gene: Myelin degeneration and its effect on T cell-mediated experimental autoimmune encephalomyelitis. Acta Neuropathologica 97 (6), S. 595 - 606 (1999)
Zeitschriftenartikel
Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: A neuroprotective role of inflammation? Journal of Experimental Medicine 189 (5), S. 865 - 870 (1999)
1998
Zeitschriftenartikel
T-cell apoptosis in inflammatory brain lesions - Destruction of T cells does not depend on antigen recognition. American Journal of Pathology 153 (3), S. 715 - 724 (1998)
