Publications of Wolfgang E. F. Klinkert

Held, K.; Bhonsle-Deeng, L.; Siewert, K.; Sato, W.; Beltran, E.; Schmidt, S.; Ruhl, G.; Ng, J. K. M.; Engerer, P.; Moser, M. et al.; Klinkert, W. E. F.; Babbe, H.; Misgeld, T.; Wekerle, H.; Laplaud, D.-A.; Hohlfeld, R.; Dornmair, K.: αβ T-cell receptors from multiple sclerosis brain lesions show MAIT cell-related features. Neurology Neuroimmunology & Neuroinflammation 2 (4), e107 (2015)

Odoardi, F.; Sie, C.; Streyl, K.; Ulaganathan, V. K.; Schlaeger, C.; Lodygin, D.; Heckelsmiller, K.; Nietfeld, W.; Ellwart, J.; Klinkert, W. E. F. et al.; Lottaz, C.; Nosov, M.; Brinkmann, V.; Spang, R.; Lehrach, H.; Vingron, M.; Wekerle, H.; Fluegel-Koch, C.; Fluegel, A.: T cells become licensed in the lung to enter the central nervous system. Nature 488 (7413), pp. 675 - 679 (2012)

Cordiglieri, C.; Odoardi, F.; Zhang, B.; Nebel, M.; Kawakami, N.; Klinkert, W. E. F.; Lodygin, D.; Luhder, F.; Breunig, E.; Schild, D. et al.; Ulaganathan, V. K.; Dornmair, K.; Dammermann, W.; Potter, B. V. L.; Guse, A. H.; Flügel, A.: Nicotinic acid adenine dinucleotide phosphate-mediated calcium signalling in effector T cells regulates autoimmunity of the central nervous system. Brain 133, pp. 1930 - 1943 (2010)

Kienast, Y.; von Baumgarten, L.; Fuhrmann, M.; Klinkert, W. E. F.; Goldbrunner, R.; Herms, J.; Winkler, F.: Real-time imaging reveals the single steps of brain metastasis formation. Nature Medicine 16 (1), pp. 116 - 122 (2010)

Bartholomäus, I.; Kawakami, N.; Odoardi, F.; Schläger, C.; Miljkovic, D.; Ellwart, J. W.; Klinkert, W. E. F.; Flügel-Koch, C.; Issekutz, T. B.; Wekerle, H. et al.; Flügel, A.: Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions. Nature 462 (7269), pp. 94 - 98 (2009)

Meilinger, D.; Fellinger, K.; Bultmann, S.; Rothbauer, U.; Bonapace, I. M.; Klinkert, W. E. F.; Spada, F.; Leonhardt, H.: Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells. EMBO Reports 10 (11), pp. 1259 - 1264 (2009)

Dorn, T.; Kuhn, U.; Bungartz, G.; Stiller, S.; Bauer, M.; Ellwart, J.; Peters, T.; Scharffetter-Kochanek, K.; Semmrich, M.; Laschinger, M. et al.; Holzmann, B.; Klinkert, W. E. F.; Straten, P. T.; Kollgaard, T.; Sixt, M.; Brakebusch, C.: RhoH and T cell development. RhoH is important for mouse thymocyte selection and T-cell receptor signaling. Blood 6, pp. 2346 - 2355 (2007)

Dorn, T.; Kuhn, U.; Bungartz, G.; Stiller, S.; Bauer, M.; Ellwart, J.; Peters, T.; Scharffetter-Kochanek, K.; Semmrich, M.; Laschinger, M. et al.; Holzmann, B.; Klinkert, W. E. F.; Straten, P. T.; Kollgaard, T.; Sixt, M.; Brakebusch, C.: RhoH is important for positive thymocyte selection and T-cell receptor signaling. Blood 109 (6), pp. 2346 - 2355 (2007)

Odoardi, F.; Kawakami, N.; Klinkert, W. E. F.; Wekerle, H.; Flügel, A.: Blood-borne soluble protein antigen intensifies T cell activation in autoimmune CNS lesions and exacerbates clinical disease. Proceedings of the National Academy of Sciences of the United States of America 104 (47), pp. 18625 - 18630 (2007)

Odoardi, F.; Kawakami, N.; Li, Z. X.; Cordiglieri, C.; Streyl, K.; Nosov, M.; Klinkert, W. E. F.; Ellwart, J. W.; Bauer, J.; Lassmann, H. et al.; Wekerle, H.; Flügel, A.: Instant effect of soluble antigen on effector T cells in peripheral immune organs during immunotherapy of autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America 104 (3), pp. 920 - 925 (2007)

Ziemssen, T.; Kümpfel, T.; Schneider, H.; Klinkert, W. E. F.; Neuhaus, O.; Hohlfeld, R.: Secretion of brain-derived neurotrophic factor by glatiramer acetate-reactive T-helper cell lines: Implications for multiple sclerosis therapy. Journal of the Neurological Sciences 233 (1-2), pp. 109 - 112 (2005)

Kawakami, N.; Lassmann, S.; Li, Z. X.; Odoardi, F.; Ritter, T.; Ziemssen, T.; Klinkert, W. E. F.; Ellwart, J. W.; Bradl, M.; Krivacic, K. et al.; Lassmann, H.; Ransohoff, R. M.; Volk, H. D.; Wekerle, H.; Linington, C.; Flügel, A.: The activation status of neuroantigen-specific T cells in the target organ determines the clinical outcome of autoimmune encephalomyelitis. Journal of Experimental Medicine 199 (2), pp. 185 - 197 (2004)

Malatesta, P.; Hack, M. A.; Hartfuss, E.; Kettenmann, H.; Klinkert, W.; Kirchhoff, F.; Götz, M.: Neuronal or glial progeny: Regional differences in radial glia fate. Neuron 37 (5), pp. 751 - 764 (2003)

Hink-Schauer, C.; Estebanez-Perpina, E.; Wilharm, E.; Fuentes-Prior, P.; Klinkert, W. E. F.; Bode, W.; Jenne, D. E.: The 2.2-angstrom crystal structure of human pro-granzyme K reveals a rigid zymogen with unusual features. Journal of Biological Chemistry 277 (52), pp. 50923 - 50933 (2002)

Ziemssen, T.; Kümpfel, T.; Klinkert, W. E. F.; Neuhaus, O.; Hohlfeld, R.: Glatiramer acetate-specific T-helper 1-and 2-type cell lines produce BDNF: Implications for multiple sclerosis therapy. Brain 125, pp. 2381 - 2391 (2002)

Flugel, A.; Matsumuro, K.; Neumann, H.; Klinkert, W. E. F.; Birnbacher, R.; Lassmann, H.; Otten, U.; Wekerle, H.: Anti-inflammatory activity of nerve growth factor in experimental autoimmune encephalomyelitis: Inhibition of monocyte transendothelial migration. European Journal of Immunology 31 (1), pp. 11 - 22 (2001)

Wiegers, G. J.; Stec, I. E. M.; Klinkert, W. E. F.; Linthorst, A. C. E.; Reul, J.: Bidirectional effects of corticosterone on splenic T-cell activation: Critical role of cell density and culture time. Neuroendocrinology 73 (2), pp. 139 - 148 (2001)

Kerschensteiner, M.; Gallmeier, E.; Behrens, L.; Vargas-Leal, V.; Misgeld, T.; Klinkert, W. E. F.; Kolbeck, R.; Hoppe, E.; Oropeza-Wekerle, R. L.; Bartke, I. et al.; Stadelmann, C.; Lassmann, H.; Wekerle, H.; Hohlfeld, R.: Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: A neuroprotective role of inflammation? Journal of Experimental Medicine 189 (5), pp. 865 - 870 (1999)

Utans-Schneitz, U.; Lorez, H.; Klinkert, W. E. F.; da Silva, J.; Lesslauer, W.: A novel rat CC chemokine, identified by targeted differential display, is upregulated in brain inflammation. Journal of Neuroimmunology 92 (1-2), pp. 179 - 190 (1998)