Publications

2025

Journal Article

Goltstein, P.; Laubender, D.; Bonhoeffer, T.; Hübener, M.: A column-like organization for ocular dominance in mouse visual cortex. Nature Communications 16, 1926 (2025)

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2024

Journal Article

Bauer, J.; Lewin, U.; Herbert, E.; Gjorgjieva, J.; Schoonover, C.; Fink, A.; Rose, T.; Bonhoeffer, T.; Hübener, M.: Sensory experience steers representational drift in mouse visual cortex. Nature Communications 15, 9153 (2024)

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Journal Article

Weiler, S.; Rahmati, V.; Isstas, M.; Wutke, J.; Stark, A. W.; Franke, C.; Graf, J.; Geis, C.; Witte, O. W.; Hübener, M. et al.; Bolz, J.; Margrie, T. W.; Holthoff, K.; Teichert, M.: A primary sensory cortical interareal feedforward inhibitory circuit for tacto-visual integration. Nature Communications 15, 3081 (2024)

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2023

Journal Article

Weiler, S.; Guggiana Nilo, D.; Bonhoeffer, T.; Hübener, M.; Rose, T.; Scheuss, V.: Functional and structural features of L2/3 pyramidal cells continuously covary with pial depth in mouse visual cortex. Cerebral Cortex 33 (7), bhac303, pp. 3715 - 3733 (2023)

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2022

Journal Article

Weiler, S.; Guggiana Nilo, D.; Bonhoeffer, T.; Hübener, M.; Rose, T.; Scheuss, V.: Orientation and direction tuning align with dendritic morphology and spatial connectivity in mouse visual cortex. Current Biology 32 (8), pp. 1743 - 1753.e7 (2022)

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2021

Journal Article

Bauer, J.; Weiler, S.; Fernholz, M. H. P.; Laubender, D.; Scheuss, V.; Hübener, M.; Bonhoeffer, T.; Rose, T.: Limited functional convergence of eye-specific inputs in the retinogeniculate pathway of the mouse. Neuron 109 (15), pp. 2457 - 2468 (2021)

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Journal Article

Glas, A.; Hübener, M.; Bonhoeffer, T.; Goltstein, P. M.: Spaced training enhances memory and prefrontal ensemble stability in mice. Current Biology 31 (18), pp. 4052 - 4061.e6 (2021)

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publisher-version

supplementary-material

Journal Article

Goltstein, P. M.; Reinert, S.; Bonhoeffer, T.; Hübener, M.: Mouse visual cortex areas represent perceptual and semantic features of learned visual categories. Nature Neuroscience 24 (10), pp. 1441 - 1451 (2021)

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Journal Article

Guggiana Nilo, D.; Riegler, C.; Hübener, M.; Engert, F.: Distributed chromatic processing at the interface between retina and brain in the larval zebrafish. Current Biology 31 (9), pp. 1945 - 1953.e5 (2021)

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Journal Article

Reinert, S.; Hübener, M.; Bonhoeffer, T.; Goltstein, P. M.: Mouse prefrontal cortex represents learned rules for categorization. Nature 593 (7859), pp. 411 - 417 (2021)

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2020

Journal Article

La Chioma, A.; Bonhoeffer, T.; Hübener, M.: Disparity sensitivity and binocular integration in mouse visual cortex areas. The Journal of Neuroscience 40 (46), pp. 8883 - 8899 (2020)

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2019

Journal Article

Glas, A.; Hübener, M.; Bonhoeffer, T.; Goltstein, P. M.: Benchmarking miniaturized microscopy against two-photon calcium imaging using single-cell orientation tuning in mouse visual cortex. PLoS One 14 (4), e0214954 (2019)

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publisher-version

Journal Article

La Chioma, A.; Bonhoeffer, T.; Hübener, M.: Area-specific mapping of binocular disparity across mouse visual cortex. Current Biology 29 (17), pp. 2954 - 2960.e5 (2019)

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2018

Journal Article

Goltstein, P. M.; Reinert, S.; Glas, A.; Bonhoeffer, T.; Hübener, M.: Food and water restriction lead to differential learning behaviors in a head-fixed two-choice visual discrimination task for mice. PLoS One 13 (9), e0204066 (2018)

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DOI

publisher-version

ZIP

Journal Article

Weiler, S.; Bauer, J.; Hübener, M.; Bonhoeffer, T.; Rose, T.; Scheuss, V.: High-yield in vitro recordings from neurons functionally characterized in vivo. Nature Protocols 13 (6), pp. 1275 - 1293 (2018)

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2017

Journal Article

Clopath, C.; Bonhoeffer, T.; Hübener, M.; Rose, T.: Variance and invariance of neuronal long-term representations. Philosophical Transactions of the Royal Society of London, Series B: Biological Sciences 372 (1715), 20160161 (2017)

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publisher-version

Journal Article

Jaepel, J.; Hübener, M.; Bonhoeffer, T.; Rose, T.: Lateral geniculate neurons projecting to primary visual cortex show ocular dominance plasticity in adult mice. Nature Neuroscience 20 (12), pp. 1708 - 1714 (2017)

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Journal Article

Keck, T.; Hübener, M.; Bonhoeffer, T.: Interactions between synaptic homeostatic mechanisms: An attempt to reconcile BCM theory, synaptic scaling, and changing excitation/inhibition balance. Current Opinion in Neurobiology 43, pp. 87 - 93 (2017)

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Journal Article

Keck, T.; Toyoizumi, T.; Chen, L.; Doiron, B.; Feldman, D. E.; Fox, K.; Gerstner, W.; Haydon, P. G.; Hübener, M.; Lee, H.-K. et al.; Lisman, J. E.; Rose, T.; Sengpiel, F.; Stellwagen, D.; Stryker, M. P.; Turrigiano, G. G.; van Rossum, M. C.: Integrating Hebbian and homeostatic plasticity: The current state of the field and future research directions. Philosophical Transactions of the Royal Society of London, Series B: Biological Sciences 372 (1715), 20160158 (2017)

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Journal Article

Rose, T.; Hübener, M.: Synapses get together for vision. Nature 547 (7664), pp. 408 - 410 (2017)

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2016

Journal Article

Falkner, S.; Grade, S.; Dimou, L.; Conzelmann, K.-K.; Bonhoeffer, T.; Goetz, M.; Hübener, M.: Transplanted embryonic neurons integrate into adult neocortical circuits. Nature 539 (7628), pp. 248 - 253 (2016)

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Journal Article

Liebscher, S.; Keller, G. B.; Goltstein, P. M.; Bonhoeffer, T.; Hübener, M.: Selective persistence of sensorimotor mismatch signals in visual cortex of behaving Alzheimer's disease mice. Current Biology 26 (7), pp. 956 - 964 (2016)

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Journal Article

Rose, T.; Jaepel, J.; Hübener, M.; Bonhoeffer, T.: Cell-specific restoration of stimulus preference after monocular deprivation in the visual cortex. Science 352 (6291), pp. 1319 - 1322 (2016)

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2014

Journal Article

Hübener, M.; Bonhoeffer, T.: Neuronal plasticity: Beyond the critical period. Cell 159 (4), pp. 727 - 737 (2014)

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Journal Article

Leinweber, M.; Zmarz, P.; Buchmann, P.; Argast, P.; Hübener, M.; Bonhoeffer, T.; Keller, G. B.: Two-photon calcium imaging in mice navigating a virtual reality environment. Journal of Visualized Experiments 84, e50885 (2014)

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Journal Article

Liebscher, S.; Page, R. M.; Käfer, K.; Winkler, E.; Quinn, K.; Goldbach, E.; Brigham, E. F.; Quincy, D.; Basi, G. S.; Schenk, D. B. et al.; Steiner, H.; Bonhoeffer, T.; Haass, C.; Meyer-Luehmann, M.; Hübener, M.: Chronic γ-secretase inhibition reduces amyloid plaque-associated instability of pre- and postsynaptic structures. Molecular Psychiatry 19 (8), pp. 937 - 946 (2014)

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Full

2013

Journal Article

Djurisic, M.; Vidal, G. S.; Mann, M.; Aharon, A.; Kim, T.; Ferrao Santos, A.; Zuo, Y.; Hübener, M.; Shatz, C. J.: PirB regulates a structural substrate for cortical plasticity. Proceedings of the National Academy of Sciences of the United States of America 110 (51), pp. 20771 - 20776 (2013)

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Journal Article

Helmchen, F.; Hübener, M.: Neuronale Netzwerke im Rampenlicht: Mit leuchtenden Proteinen zelluläre Aktivitätsmuster entschlüsseln. Neuroforum 13 (2), pp. 47 - 55 (2013)

MPG.PuRe

Journal Article

Keck, T.; Keller, G. B.; Jacobsen, R. I.; Eysel, U. T.; Bonhoeffer, T.; Hübener, M.: Synaptic scaling and homeostatic plasticity in the mouse visual cortex in vivo. Neuron 80 (2), pp. 327 - 334 (2013)

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Journal Article

McCarter, J. F.; Liebscher, S.; Bachhuber, T.; Abou-Ajram, C.; Hübener, M.; Hyman, B. T.; Haass, C.; Meyer-Luehmann, M.: Clustering of plaques contributes to plaque growth in a mouse model of Alzheimer's disease. Acta Neuropathologica 126 (2), pp. 179 - 188 (2013)

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Full

Journal Article

Tomita, K.; Sperling, M.; Cambridge, S. B.; Bonhoeffer, T.; Hübener, M.: A molecular correlate of ocular dominance columns in the developing mammalian visual cortex. Cerebral Cortex 23 (11), pp. 2531 - 2541 (2013)

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2012

Journal Article

Ertürk, A.; Mauch, C. P.; Hellal, F.; Förstner, F.; Keck, T.; Becker, K.; Jaehrling, N.; Steffens, H.; Richter, M.; Hübener, M. et al.; Kramer, E.; Kirchhoff, F.; Dodt, H. U.; Bradke, F.: Three-dimensional imaging of the unsectioned adult spinal cord to assess axon regeneration and glial responses after injury. Nature Medicine 18 (1), pp. 166 - 171 (2012)

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Journal Article

Keller, G. B.; Bonhoeffer, T.; Hübener, M.: Sensorimotor mismatch signals in primary visual cortex of the behaving mouse. Neuron 74 (5), pp. 809 - 815 (2012)

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Journal Article

Levelt, C. N.; Hübener, M.: Critical-period plasticity in the visual cortex. Annual Review of Neuroscience 35, pp. 309 - 330 (2012)

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2011

Journal Article

Keck, T.; Scheuss, V.; Jacobsen, R. I.; Wierenga, C. J.; Eysel, U. T.; Bonhoeffer, T.; Hübener, M.: Loss of sensory input causes rapid structural changes of inhibitory neurons in adult mouse visual cortex. Neuron 71 (5), pp. 869 - 882 (2011)

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Journal Article

Kreile, A. K.; Bonhoeffer, T.; Hübener, M.: Altered visual experience induces instructive changes of orientation preference in mouse visual cortex. The Journal of Neuroscience 31 (39), pp. 13911 - 13920 (2011)

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2010

Journal Article

Hübener, M.; Bonhoeffer, T.: Searching for Engrams. Neuron 67 (3), pp. 363 - 371 (2010)

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2009

Journal Article

Hofer, S. B.; Mrsic-Flogel, T. D.; Bonhoeffer, T.; Hübener, M.: Experience leaves a lasting structural trace in cortical circuits. Nature 457 (7227), pp. 313 - 317 (2009)

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Journal Article

Holtmaat, A.; Bonhoeffer, T.; Chow, D. K.; Chuckowree, J.; De Paola, V.; Hofer, S. B.; Hübener, M.; Keck, T.; Knott, G.; Lee, W. C. A. et al.; Mostany, R.; Mrsic-Flogel, T. D.; Nedivi, E.; Portera-Cailliau, C.; Svoboda, K.; Trachtenberg, J. T.; Wilbrecht, L.: Long-term, high-resolution imaging in the mouse neocortex through a chronic cranial window. Nature Protocols 4 (8), pp. 1128 - 1144 (2009)

MPG.PuRe

DOI

2008

Journal Article

Keck, T.; Mrsic-Flogel, T. D.; Afonso, M. V.; Eysel, U. T.; Bonhoeffer, T.; Hübener, M.: Massive restructuring of neuronal circuits during functional reorganization of adult visual cortex. Nature Neuroscience 11 (10), pp. 1162 - 1167 (2008)

MPG.PuRe

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Journal Article

Mank, M.; Ferrao Santos, A.; Direnberger, S.; Mrsic-Flogel, T. D.; Hofer, S. B.; Stein, V.; Hendel, T.; Reiff, D. F.; Levelt, C.; Borst, A. et al.; Bonhoeffer, T.; Hübener, M.; Griesbeck, O.: A genetically encoded calcium indicator for chronic in vivo two-photon imaging. Nature Methods 5 (9), pp. 805 - 811 (2008)

MPG.PuRe

DOI

2007

Journal Article

Mrsic-Flogel, T. D.; Hofer, S. B.; Ohki, K.; Reid, R. C.; Bonhoeffer, T.; Hübener, M.: Homeostatic regulation of eye-specific responses in visual cortex during ocular dominance plasticity. Neuron 54 (6), pp. 961 - 972 (2007)

MPG.PuRe

DOI

2006

Journal Article

Hofer, S. B.; Mrsic-Flogel, T. D.; Bonhoeffer, T.; Hübener, M.: Lifelong learning: Ocular dominance plasticity in mouse visual cortex. Current Opinion in Neurobiology 16 (4), pp. 451 - 459 (2006)

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Journal Article

Hofer, S. B.; Mrsic-Flogel, T. D.; Bonhoeffer, T.; Hübener, M.: Prior experience enhances plasticity in adult visual cortex. Nature Neuroscience 9 (1), pp. 127 - 132 (2006)

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Journal Article

Ohki, K.; Chung, S. Y.; Kara, P.; Hübener, M.; Bonhoeffer, T.; Reid, R. C.: Highly ordered arrangement of single neurons in orientation pinwheels. Nature 442 (7105), pp. 925 - 928 (2006)

MPG.PuRe

DOI

2005

Journal Article

Hübener, M.; Bonhoeffer, T.: Visual cortex: Two-photon excitement. Current Biology 15 (6), pp. R205 - R208 (2005)

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Journal Article

Mrsic-Flogel, T. D.; Hofer, S. B.; Creutzfeldt, C.; Cloëz-Tayarani, I.; Changeux, J.-P.; Bonhoeffer, T.; Hübener, M.: Altered map of visual space in the superior colliculus of mice lacking early retinal waves. The Journal of Neuroscience 25 (29), pp. 6921 - 6928 (2005)

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2003

Journal Article

Hübener, M.: Mouse visual cortex. Current Opinion in Neurobiology 13 (4), pp. 413 - 420 (2003)

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Journal Article

Mrsic-Flogel, T.; Hübener, M.; Bonhoeffer, T.: Brain mapping: New wave optical imaging. Current Biology 13 (19), pp. R778 - R780 (2003)

MPG.PuRe

DOI

2002