Publications of Gurumoorthy Krishnamoorthy

Mues, M.; Krishnamoorthy, G.: BReDi mouse: A novel transgenic mouse strain to track and deplete Bcells. European Journal of Immunology 49 (3), pp. 500 - 503 (2019)

Berer, K.; Martinez, I.; Walker, A.; Kunkel, B.; Schmitt-Kopplin, P.; Walter, J.; Krishnamoorthy, G.: Dietary non-fermentable fiber prevents autoimmune neurological disease by changing gut metabolic and immune status. Scientific Reports 8, 10431 (2018)

Spadaro, M.; Winklmeier, S.; Beltran, E.; Macrini, C.; Hoeftberger, R.; Schuh, E.; Thaler, F. S.; Gerdes, L. A.; Laurent, S.; Gerhards, R. et al.; Braendle, S.; Dornmair, K.; Breithaupt, C.; Krumbholz, M.; Moser, M.; Krishnamoorthy, G.; Kamp, F.; Jenne, D. E.; Hohlfeld, R.; Kuempfel, T.; Lassmann, H.; Kawakami, N.; Meinl, E.: Pathogenicity of human antibodies against myelin oligodendrocyte glycoprotein. Annals of Neurology 84 (2), pp. 315 - 328 (2018)

Berer, K.; Gerdes, L. A.; Cekanaviciute, E.; Jia, X.; Xiao, L.; Xia, Z.; Liu, C.; Klotz, L.; Stauffer, U.; Baranzini, S. E. et al.; Kuempfel, T.; Hohlfeld, R.; Krishnamoorthy, G.; Wekerle, H.: Gut microbiota from multiple sclerosis patients enables spontaneous autoimmune encephalomyelitis in mice. Proceedings of the National Academy of Sciences of the United States of America 114 (40), pp. 10719 - 10724 (2017)

Rumble, J. M.; Huber, A. K.; Krishnamoorthy, G.; Srinivasan, A.; Giles, D. A.; Zhang, X.; Wang, L.; Segal, B. M.: Neutrophil-related factors as biomarkers in EAE and MS. Journal of Experimental Medicine 212 (1), pp. 23 - 35 (2015)

Ben-Nun, A.; Kaushansky, N.; Kawakami, N.; Krishnamoorthy, G.; Berer, K.; Liblau, R.; Hohlfeld, R.; Wekerle, H.: From classic to spontaneous and humanized models of multiple sclerosis: Impact on understanding pathogenesis and drug development. Journal of Autoimmunity 54, pp. 33 - 50 (2014)

Berer, K.; Boziki, M.; Krishnamoorthy, G.: Selective accumulation of pro-inflammatory T cells in the intestine contributes to the resistance to autoimmune demyelinating disease. PLoS One 9 (2), e87876 (2014)

Berer, K.; Krishnamoorthy, G.: Microbial view of central nervous system autoimmunity. FEBS LETTERS 588 (22), pp. 4207 - 4213 (2014)

Eberle, M.; Ebel, P.; Wegner, M.-S.; Maennich, J.; Tafferner, N.; Ferreiros, N.; Birod, K.; Schreiber, Y.; Krishnamoorthy, G.; Willecke, K. et al.; Geisslinger, G.; Groesch, S.; Schiffmann, S.: Regulation of ceramide synthase 6 in a spontaneous experimental autoimmune encephalomyelitis model is sex dependent. Biochemical Pharmacology 92 (2), pp. 326 - 335 (2014)

Koutrolos, M.; Berer, K.; Kawakami, N.; Wekerle, H.; Krishnamoorthy, G.: Treg cells mediate recovery from EAE by controlling effector T cell proliferation and motility in the CNS. Acta Neuropathologica Communications 2, 163 (2014)

Nischwitz, S.; Faber, H.; Saemann, P. G.; Domingues, H. S.; Krishnamoorthy, G.; Knop, M.; Mueller-Sarnowski, F.; Yassouridis, A.; Weber, F.: Interferon-1a reduces increased interleukin-16 levels in multiple sclerosis patients. Acta Neurologica Scandinavica 130 (1), pp. 46 - 52 (2014)

Mues, M.; Bartholomäus, I.; Thestrup, T.; Griesbeck, O.; Wekerle, H.; Kawakami, N.; Krishnamoorthy, G.: Real-time in vivo analysis of T cell activation in the central nervous system using a genetically encoded calcium indicator. Nature Medicine 19 (6), pp. 778 - 783 (2013)

Wekerle, H.; Berer, K.; Krishnamoorthy, G.: Remote control - triggering of brain autoimmune disease in the gut. Current Opinion in Immunology 25 (6), pp. 683 - 689 (2013)

Berer, K.; Krishnamoorthy, G.: Commensal gut flora and brain autoimmunity: A love or hate affair? Acta Neuropathologica (Berl) 123 (5), pp. 639 - 651 (2012)

Direnberger, S.; Mues, M.; Micale, V.; Wotjak, C. T.; Dietzel, S.; Schubert, M.; Scharr, A.; Hassan, S.; Wahl-Schott, C.; Biel, M. et al.; Krishnamoorthy, G.; Griesbeck, O.: Biocompatibility of a genetically encoded calcium indicator in a transgenic mouse model. Nature Communications 3, 1031 (2012)

Wekerle, H.; Krishnamoorthy, G.: Brain Autoimmunity: The CD8 Question(s). Immunity 37 (1), pp. 8 - 10 (2012)

Berer, K.; Mues, M.; Koutrolos, M.; Al Rasbi, Z.; Boziki, M.; Johner, C.; Wekerle, H.; Krishnamoorthy, G.: Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination. Nature 479 (7374), pp. 538 - 541 (2011)

Berer, K.; Wekerle, H.; Krishnamoorthy, G.: B cells in spontaneous autoimmune diseases of the central nervous system. Molecular Immunology 48 (11), pp. 1332 - 1337 (2011)

Fitzner, D.; Schnaars, M.; van Rossum, D.; Krishnamoorthy, G.; Dibaj, P.; Bakhti, M.; Regen, T.; Hanisch, U. K.; Simons, M.: Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis. Journal of Cell Science 124 (3), pp. 447 - 458 (2011)

Varadarajulu, J.; Lebar, M.; Krishnamoorthy, G.; Habelt, S.; Lu, J.; Weinstein, I. B.; Li, H. Y.; Holsboer, F.; Turck, C. W.; Touma, C.: Increased anxiety-related behaviour in Hint1 knockout mice. Behavioural Brain Research 220 (2), pp. 305 - 311 (2011)

Domingues, H. S.; Mues, M.; Lassmann, H.; Wekerle, H.; Krishnamoorthy, G.: Functional and pathogenic differences of Th1 and Th17 cells in experimental autoimmune encephalomyelitis. PLoS One 5 (11), e15531 (2010)

Krishnamoorthy, G.; Saxena, A.; Mars, L. T.; Domingues, H. S.; Ben-Nun, A.; Lassmann, H.; Dornmair, K.; Mentele, R.; Kurschus, F. C.; Liblau, R. S. et al.; Wekerle, H.: Myelin-specific T cells also recognize neuronal autoantigen in a transgenic mouse model of multiple sclerosis. Nature Medicine 15 (6), pp. 626 - 632 (2009)

Krishnamoorthy, G.; Wekerle, H.: EAE: An immunologist's magic eye. European Journal of Immunology 39 (8), pp. 2031 - 2035 (2009)

Pöllinger, B.; Krishnamoorthy, G.; Berer, K.; Lassmann, H.; Bösl, M. R.; Dunn, R.; Domingues, H. S.; Holz, A.; Kurschus, F. C.; Wekerle, H.: Spontaneous relapsing-remitting EAE in the SJL/J mouse: MOG-reactive transgenic T cells recruit endogenous MOG-specific B cells. Journal of Experimental Medicine 206 (6), pp. 1303 - 1316 (2009)

Krishnamoorthy, G.; Holz, A.; Wekerle, H.: Experimental models of spontaneous in the central nervous system. Journal of Molecular Medicine-JMM 85 (11), pp. 1161 - 1173 (2007)

Krishnamoorthy, G.; Lassmann, H.; Wekerle, H.; Holz, A.: Spontaneous opticospinal encephalomyelitis in a double-transgenic mouse model of autoimmune T cell B cell cooperation. The Journal of Clinical Investigation 116 (9), pp. 2385 - 2392 (2006)

Krishnamoorthy, G.: Devic mouse: A sponeaneous double-transgenic mouse model of human opticospinal multiple sclerosis and autoimmune T- B cell cooperation. Dissertation, Ludwig-Maximilians-Universität, München (2007)

Krishnamoorthy, G.: Modeling central nervous system autoimmunity: Triggers and pathogenic processes. Habilitation, Ludwig-Maximilians-Universität, München (2015)