Publications of Angelika Harbauer

Hees, J. T.; Segura, I.; Schneider, A.; Schifferer, M.; Misgeld, T.; Harbauer, A.: ER-associated biogenesis of PINK1 preprotein for neuronal mitophagy. bioRxiv: the preprint server for biology (2025)

Hees, J. T.; Wanderoy, S.; Lindner, J.; Helms, M.; Murali Mahadevan, H.; Harbauer, A.: Insulin signalling regulates Pink1 mRNA localization via modulation of AMPK activity to support PINK1 function in neurons. Nature Metabolism 6 (3), pp. 514 - 530 (2024)

Mauker, P.; Beckmann, D.; Kitowski, A.; Heise, C.; Wientjens, C.; Davidson, A. J.; Wanderoy, S.; Fabre, G.; Harbauer, A.; Wood, W. et al.; Wilhelm, C.; Thorn-Seshold, J.; Misgeld, T.; Kerschensteiner, M.; Thorn-Seshold, O.: Fluorogenic chemical probes for wash-free imaging of cell membrane damage in ferroptosis, necrosis, and axon injury. Journal of the American Chemical Society 146 (16), pp. 11072 - 11082 (2024)

Harbauer, A. B.; Hees, J. T.; Wanderoy, S.; Segura, I.; Gibbs, W.; Cheng, Y.; Ordonez, M.; Cai, Z.; Cartoni, R.; Ashrafi, G. et al.; Wang, C.; Perocchi, F.; He, Z.; Schwarz, T. L.: Neuronal mitochondria transport Pink1 mRNA via synaptojanin 2 to support local mitophagy. Neuron 110 (9), pp. 1516 - 1531.e9 (2022)

Strohm, L.; Hu, Z.; Suk, Y.; Rühmkorf, A.; Sternburg, E.; Gattringer, V.; Riemenschneider, H.; Berutti, R.; Graf, E.; Weishaupt, J. H. et al.; Brill, M. S.; Harbauer, A. B.; Dormann, D.; Dengjel, J.; Edbauer, D.; Behrends, C.: Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants. Life science alliance 5 (11), e202101327 (2022)

Wanderoy, S.; Rühmkorf, A.; Harbauer, A. B.: Microfluidics-assisted selective depolarization of axonal mitochondria. Journal of Visualized Experiments 186, e64196 (2022)

Kravic, B.; Harbauer, A. B.; Romanello, V.; Simeone, L.; Vögtle, F. N.; Kaiser, T.; Straubinger, M.; Huraskin, D.; Böttcher, M.; Cerqua, C. et al.; Martin, E. D.; Poveda-Huertes, D.; Buttgereit, A.; Rabalski, A. J.; Heuss, D.; Rudolf, R.; Friedrich, O.; Litchfield, D.; Marber, M.; Salviati, L.; Mougiakakos, D.; Neuhuber, W.; Sandri, M.; Meisinger, C.; Hashemolhosseini, S.: In mammalian skeletal muscle, phosphorylation of TOMM22 by protein kinase CSNK2/CK2 controls mitophagy. Autophagy 14 (2), pp. 311 - 335 (2018)

Harbauer, A. B.: Mitochondrial health maintenance in axons. Biochemical Society Transactions 45, pp. 1045 - 1052 (2017)

Harbauer, A. B.; Opalinska, M.; Gerbeth, C.; Herman, J. S.; Rao, S.; Schönfisch, B.; Guiard, B.; Schmidt, O.; Pfanner, N.; Meisinger, C.: Cell cycle-dependent regulation of mitochondrial preprotein translocase. Science 346 (6213), pp. 1109 - 1113 (2014)

Harbauer, A. B.; Zahedi, R. P.; Sickmann, A.; Pfanner, N.; Meisinger, C.: The protein import machinery of mitochondria - A regulatory hub in metabolism, stress, and disease. Cell Metabolism 19 (3), pp. 357 - 372 (2014)

Gerbeth, C.; Schmidt, O.; Rao, S.; Harbauer, A. B.; Mikropoulou, D.; Opalinska, M.; Guiard, B.; Pfanner, N.; Meisinger, C.: Glucose-induced regulation of protein import receptor Tom22 by cytosolic and mitochondria-bound kinases. Cell Metabolism 18 (4), pp. 578 - 587 (2013)

Rao, S.; Schmidt, O.; Harbauer, A. B.; Schönfisch, B.; Guiard, B.; Pfanner, N.; Meisinger, C.: Biogenesis of the preprotein translocase of the outer mitochondrial membrane: Protein kinase A phosphorylates the precursor of Tom40 and impairs its import. Molecular Biology of the Cell 23 (9), pp. 1618 - 1627 (2012)

Rao, S.; Gerbeth, C.; Harbauer, A. B.; Mikropoulou, D.; Meisinger, C.; Schmidt, O.: Signaling at the gate: Phosphorylation of the mitochondrial protein import machinery. Cell Cycle 10 (13), pp. 2083 - 2090 (2011)

Schmidt, O.; Harbauer, A. B.; Rao, S.; Eyrich, B.; Zahedi, R. P.; Stojanovski, D.; Schönfisch, B.; Guiard, B.; Sickmann, A.; Pfanner, N. et al.; Meisinger, C.: Regulation of mitochondrial protein import by cytosolic kinases. Cell 144 (2), pp. 227 - 239 (2011)

Hees, J. T.; Harbauer, A. B.: Live-cell imaging of RNA transport in axons of cultured primary neurons. In: Axonal transport. Methods and protocols, 1 Ed., pp. 225 - 237 (Ed. Vagnoni, A.). Humana, New York (2022)

Harbauer, A. B.; Schwarz, T. L.: Mitochondrial hitch-hiking of Pink1 mRNA supports axonal mitophagy. Autophagy 18 (12), pp. 3048 - 3049 (2022)

Segura, I.; Harbauer, A.: The role of mitochondrial RNA association for mitochondrial homeostasis in neurons. Biochemical Journal 481 (3), pp. 119 - 139 (2024)

Rühmkorf, A.; Harbauer, A. B.: Role of mitochondria-ER contact sites in mitophagy. Biomolecules 13 (8), 1198 (2023)

Harbauer, A. B.; Schneider, A.; Wohlleber, D.: Analysis of mitochondria by single-organelle resolution. Annual review of analytical chemistry 15, pp. 1 - 16 (2022)

Hees, J. T.; Harbauer, A. B.: Metabolic regulation of mitochondrial protein biogenesis from a neuronal perspective. Biomolecules 12 (11), 1595 (2022)

Heger, L. M.; Wise, R. M.; Hees, J. T.; Harbauer, A. B.; Burbulla, L. F.: Mitochondrial phenotypes in Parkinson's diseases – A focus on human iPSC-derived dopaminergic neurons. Cells 10 (12), 3436 (2021)

Murali Mahadevan, H.; Hashemiaghdam, A.; Ashrafi, G.; Harbauer, A. B.: Mitochondria in neuronal health: From energy metabolism to Parkinson's disease. Advanced Biology 5 (9), 2100663 (2021)

Wanderoy, S.; Hees, J. T.; Klesse, R.; Edlich, F.; Harbauer, A. B.: Kill one or kill the many: Interplay between mitophagy and apoptosis. Biological Chemistry 402 (1), pp. 73 - 88 (2021)

Hees, J. T.; Harbauer, A. B.: Calcium dysregulation and mitochondrial dysfunction form a vicious cycle in Parkinson’s disease. American Journal of Biomedical Science & Research 5 (3), AJBSR.MS.ID.000920 (2019)