Publications of the emeritus-department "Neuroimmunology"

Abdul-Majid, K. B.; Stefferl, A.; Bourquin, C.; Lassmann, H.; Linington, C.; Olsson, T.; Kleinau, S.; Harris, R. A.: Fc receptors are critical for autoimmune inflammatory damage to the central nervous system in experimental autoimmune encephalomyelitis. Scandinavian Journal of Immunology 55 (1), pp. 70 - 81 (2002)

Andersson, M.; Yu, M.; Soderstrom, M.; Weerth, S.; Baig, S.; Linington, C.; Solders, G.; Link, H.: Multiple MAG peptides are recognized by circulating T and B lymphocytes in polyneuropathy and multiple sclerosis. European Journal of Neurology 9 (3), pp. 243 - 251 (2002)

Bauer, J.; Bradl, M.; Klein, M.; Leisser, M.; Deckwerth, T. L.; Wekerle, H.; Lassmann, H.: Endoplasmic reticulum stress in PLP-overexpressing transgenic rats: Gray matter oligodendrocytes are more vulnerable than white matter oligodendrocytes. Journal of Neuropathology and Experimental Neurology 61 (1), pp. 12 - 22 (2002)

Berninger, B.; Bi, G. Q.: Synaptic modification in neural circuits: A timely action. Bioessays 24 (3), pp. 212 - 222 (2002)

Bradl, M.; Flügel, A.: The role of T cells in brain pathology. Curr Top Microbiol Immunol. 265, pp. 141 - 162 (2002)

Burger, B.; Uhlhaas, S.; Mangold, E.; Propping, P.; Friedl, W.; Jenne, D. E.; Dockter, G.; Back, W.: Novel de novo mutation of MADH4/SMAD4 in a patient with juvenile polyposis. American Journal of Medical Genetics 110 (3), pp. 289 - 291 (2002)

Campbell, P. K.; Waymire, K. G.; Heier, R. L.; Sharer, C.; Day, D. E.; Reimann, H.; Jaje, J. M.; Friedrich, G. A.; Burmeister, M.; Bartness, T. J. et al.; Russell, L. D.; Young, L. J.; Zimmer, M.; Jenne, D. E.; MacGregor, G. R.: Mutation of a novel gene results in abnormal development of spermatid flagella, loss of intermale aggression and reduced body fat in mice. Genetics 162 (1), pp. 307 - 320 (2002)

Clanet, M.; Radue, E. W.; Kappos, L.; Hartung, H. P.; Hohlfeld, R.; Sandberg-Wollheim, M.; Kooijmans-Coutinho, M. F.; Tsao, E. C.; Sandrock, A. W.; European IFNß-1a (Avonex) Dose-Comparison Study Investigators: A randomised, double-blind, dose-comparison study of weekly interferon ß-1a in relapsing MS. Neurology 59 (10), pp. 1507 - 1517 (2002)

Farina, C.; Vargas-Leal, V.; Heydari, N.; Kümpfel, T.; Meinl, E.; Hohlfeld, R.: Treatment with glatiramer acetate induces specific IgG4 antibodies in multiple sclerosis patients. Journal of Neuroimmunology 123 (1-2), pp. 188 - 192 (2002)

Farina, C.; Wagenpfeil, S.; Hohlfeld, R.: Immunological assay for assessing the efficacy of glatiramer acetate (Copaxone) in multiple sclerosis - A pilot study. Journal of Neurology 249 (11), pp. 1587 - 1592 (2002)

Gold, R.; Linington, C.: Devic's disease: Bridging the gap between laboratory and clinic. Brain 125, pp. 1425 - 1427 (2002)

Hammer, M. H.; Schroder, G.; Risch, K.; Flügel, A.; Volk, H. D.; Lehmann, M.; Ritter, T.: Antigen-dependent transgene expression in kidney transplantation: A novel approach using gene-engineered T lymphocytes. Journal of the American Society of Nephrology 13 (2), pp. 511 - 518 (2002)

Hink-Schauer, C.; Estebanez-Perpina, E.; Wilharm, E.; Fuentes-Prior, P.; Klinkert, W. E. F.; Bode, W.; Jenne, D. E.: The 2.2-angstrom crystal structure of human pro-granzyme K reveals a rigid zymogen with unusual features. Journal of Biological Chemistry 277 (52), pp. 50923 - 50933 (2002)

Hohlfeld, R.: Myelin failure in multiple sclerosis: Breaking the spell of Notch. Nature Medicine 8 (10), pp. 1075 - 1076 (2002)

Hohlfeld, R.: How promising is hematopoetic stem cell transplantation in multiple sclerosis? J Neurol. 249, pp. 1147 - 1149 (2002)

Jishage, K.; Nezu, J.; Kawase, Y.; Iwata, T.; Watanabe, M.; Miyoshi, A.; Ose, A.; Habu, K.; Kake, T.; Kamada, N. et al.; Ueda, O.; Kinoshita, M.; Jenne, D. E.; Shimane, M.; Suzuki, H.: Role of Lkb1, the causative gene of Peutz-Jegher's syndrome, in embryogenesis and polyposis. Proceedings of the National Academy of Sciences of the United States of America 99 (13), pp. 8903 - 8908 (2002)

Kirchhoff, S.; Sebens, T.; Baumann, S.; Krueger, A.; Zawatzky, R.; Min, L. W.; Meinl, E.; Neipel, F.; Fleckenstein, B.; Krammer, P. H.: Viral IFN-regulatory factors inhibit activation-induced cell death via two positive regulatory IFN-Regulatory factor 1- dependent domains in the CD95 ligand promoter. Journal of Immunology 168 (3), pp. 1226 - 1234 (2002)

Meinl, E.; Hohlfeld, R.: Immunopathogenesis of multiple sclerosis: MBP and beyond. Clinical and Experimental Immunology 128 (3), pp. 395 - 397 (2002)

Neumann, H.; Schweigreiter, R.; Yamashita, T.; Rosenkranz, K.; Wekerle, H.; Barde, Y. A.: Tumor necrosis factor inhibits neurite outgrowth and branching of hippocampal neurons by a Rho-dependent mechanism. The Journal of Neuroscience 22 (3), pp. 854 - 862 (2002)

Popovic, N.; Schubart, A.; Goetz, B. D.; Zhang, S. C.; Linington, C.; Duncan, I. D.: Inhibition of autoimmune encephalomyelitis by a tetracycline. Annals of Neurology 51 (2), pp. 215 - 223 (2002)

Scolding, N. J.; Wilson, H.; Hohlfeld, R.; Polman, C.; Leite, I.; Gilhus, N.; The EFNS Crebral Vasculitis Task Force: The recognition, diagnosis and management of cerebral vasculitis: A European survey. European Journal of Neurology 9 (4), pp. 343 - 347 (2002)

Stadelmann, C.; Kerschensteiner, M.; Misgeld, T.; Bruck, W.; Hohlfeld, R.; Lassmann, H.: BDNF and gp145trkB in multiple sclerosis brain lesions: Neuroprotective interactions between immune and neuronal cells? Brain 125, pp. 75 - 85 (2002)

Storch, M. K.; Weissert, R.; Stefferl, A.; Birnbacher, R.; Wallstrom, E.; Dahlman, I.; Ostensson, C. G.; Linington, C.; Olsson, T.; Lassmann, H.: MHC gene related effects on microglia and macrophages in experimental autoimmune encephalomyelitis determine the extent of axonal injury. Brain Pathology 12 (3), pp. 287 - 299 (2002)

Weidinger, G.: Measles virus-specific T-cell immunity in rodent models. Viral Immunology 15 (3), pp. 429 - 434 (2002)

Wekerle, H.: Immune protection of the brain - Efficient and delicate. The Journal of Infectious Diseases 186 (Suppl. 2), pp. S140 - S144 (2002)

Wekerle, H.: Tackling multiple sclerosis. Nature 420 (6911), pp. 39 - 40 (2002)

Wiendl, H.; Hohlfeld, R.: Therapeutic approaches in multiple sclerosis - Lessons from failed and interrupted treatment trials. Biodrugs 16 (3), pp. 183 - 200 (2002)

Wiendl, H.; Malotka, J.; Holzwarth, B.; Weltzien, H. U.; Wekerle, H.; Hohlfeld, R.; Dornmair, K.: An autoreactive gamma delta TCR derived from a polymyositis lesion. Journal of Immunology 169 (1), pp. 515 - 521 (2002)

Ziemssen, T.; Kümpfel, T.; Klinkert, W. E. F.; Neuhaus, O.; Hohlfeld, R.: Glatiramer acetate-specific T-helper 1-and 2-type cell lines produce BDNF: Implications for multiple sclerosis therapy. Brain 125, pp. 2381 - 2391 (2002)

Ziemssen, T.; Neuhaus, O.; Farina, C.; Hartung, H. P.; Hohlfeld, R.: Treatment of multiple sclerosis with glatiramer acetate - new information about its mechanisms of action, pharmacokinetics, adverse effects and clinical studies. Nervenarzt 73 (4), pp. 321 - 331 (2002)

Ziemssen, T.; Neuhaus, O.; Hohlfeld, R.: Risk-benefit assessment of glatiramer acetate in multiple sclerosis. Drug Safety 24 (13), pp. 979 - 990 (2002)

Dechant, G.; Neumann, H.: Neurotrophins. In: Molecular and Cellular Biology of Neuroprotection in the CNS, Vol. 513, pp. 303 - 334 (Ed. Alzheimer, C.) (2002)

Derfuss, T.; Meinl, E.: Herpesviral proteins regulating apoptosis. In: VIRAL PROTEINS COUNTERACTING HOST DEFENSES, pp. 257 - 272. SPRINGER-VERLAG BERLIN, BERLIN (2002)

Pfister, H.: Wegener’sche Granulomatose: Untersuchungen zur Rolle zytoplasmatischer Neutrophilen-Autoantikörper und deren Zielantigen Proteinase 3 sowie Neutrophilen-Elastase bei Entzündungsprozessen in der Maus. Dissertation, Julius-Maximilians-Universität, Würzburg (2002)

Schubart, A.: Aspects of the Immunobiology of Myelin Oligodendrocyte Glycoprotein (MOG)-induced Experimental Autoimmune Encephalomyelitis (EAE). Dissertation, Ludwig-Maximilians-Universität, München (2002)

Bradl, M.: Die Entwicklung autoimmuner T-Zellen und deren Interaktionen mit dem Zentralnervensystem: Untersuchungen im Tiermodell der experimentellen autoimmunen Enzephalomyelitis. Habilitation, Ludwig-Maximilians-Universität, München (2002)