Publications of the emeritus-department "Neuroimmunology"

Berer, K.; Krishnamoorthy, G.: Commensal gut flora and brain autoimmunity: A love or hate affair? Acta Neuropathologica (Berl) 123 (5), pp. 639 - 651 (2012)

Bruder, J.; Siewert, K.; Obermeier, B.; Malotka, J.; Scheinert, P.; Kellermann, J.; Ueda, T.; Hohlfeld, R.; Dornmair, K.: Target specificity of an autoreactive pathogenic human gamma delta-T cell receptor in myositis. The Journal of Biological Chemistry 287 (25), pp. 20986 - 20995 (2012)

Colombo, E.; Cordiglieri, C.; Melli, G.; Newcombe, J.; Krumbholz, M.; Parada, L. F.; Medico, E.; Hohlfeld, R.; Meinl, E.; Farina, C.: Stimulation of the neurotrophin receptor TrkB on astrocytes drives nitric oxide production and neurodegeneration. Journal of Experimental Medicine 209 (3), pp. 521 - 535 (2012)

Derfuss, T.; Meinl, E.: Identifying autoantigens in demyelinating diseases: Valuable clues to diagnosis and treatment? Current Opinion in Neurology 25 (3), pp. 231 - 238 (2012)

Direnberger, S.; Mues, M.; Micale, V.; Wotjak, C. T.; Dietzel, S.; Schubert, M.; Scharr, A.; Hassan, S.; Wahl-Schott, C.; Biel, M. et al.; Krishnamoorthy, G.; Griesbeck, O.: Biocompatibility of a genetically encoded calcium indicator in a transgenic mouse model. Nature Communications 3, 1031 (2012)

Eisele, S.; Krumbholz, M.; Fischer, M.-T.; Mohan, H.; Junker, A.; Arzberger, T.; Hohlfeld, R.; Bradl, M.; Lassmann, H.; Meinl, E.: Prospects of transcript profiling for mRNAs and microRNAs using formalin fixed and paraffin embedded dissected autoptic multiple sclerosis lesions. Brain Pathology 22, pp. 607 - 618 (2012)

Eisele, S.; Krumbholz, M.; Fischer, M.-T.; Mohan, H.; Junker, A.; Arzberger, T.; Hohlfeld, R.; Bradl, M.; Lassmann, H.; Meinl, E.: Prospects of transcript profiling for mRNAs and microRNAs using formalin-fixed and paraffin-embedded dissected autoptic multiple sclerosis lesions. Brain Pathology 22 (5), pp. 607 - 618 (2012)

Elliott, C.; Lindner, M.; Arthur, A.; Brennan, K.; Jarius, S.; Hussey, J.; Chan, A.; Stroet, A.; Olsson, T.; Willison, H. et al.; Barnett, S. C.; Meinl, E.; Linington, C.: Functional identification of pathogenic autoantibody responses in patients with multiple sclerosis. Brain 135, pp. 1819 - 1833 (2012)

Hedberg, C.; Melberg, A.; Kuhl, A.; Jenne, D. E.; Oldfors, A.: Autosomal dominant myofibrillar myopathy with arrhythmogenic right ventricular cardiomyopathy 7 is caused by a DES mutation. European journal of human genetics 20 (9), pp. 984 - 985 (2012)

Held, K.; Eiglmeier, I.; Himmelein, S.; Sinicina, I.; Brandt, T.; Theil, D.; Dornmair, K.; Derfuss, T.: Clonal expansions of CD8(+) T cells in latently HSV-1-infected human trigeminal ganglia. Journal of NeuroVirology 18 (1), pp. 62 - 68 (2012)

Hohlfeld, R.: Ion channels boost axonal injury in multiple sclerosis. Nature Medicine 18 (12), pp. 1743 - 1745 (2012)

Hohlfeld, R.; Wekerle, H.: β-Amyloid: Enemy or remedy? Science translational medicine: Integrating medicine and science 4 (145), 145fs24 (2012)

Kawakami, N.; Bartholomäus, I.; Pesic, M.; Mues, M.: An autoimmunity odyssey: How autoreactive T cells infiltrate into the CNS. Immunological Reviews 248 (Sp. Iss.), pp. 140 - 155 (2012)

Kim, S.-M.; Bhonsle, L.; Besgen, P.; Nickel, J.; Backes, A.; Held, K.; Vollmer, S.; Dornmair, K.; Prinz, J. C.: Analysis of the paired TCR α- and β-chains of single human T cells. PLoS One 7 (5), e37338 (2012)

Krumbholz, M.; Derfuss, T.; Hohlfeld, R.; Meinl, E.: B cells and antibodies in multiple sclerosis pathogenesis and therapy. Nature Reviews Neurology 8 (11), pp. 613 - 623 (2012)

Lippok, S.; Seidel, S. A. I.; Duhr, S.; Uhland, K.; Holthoff, H.-P.; Jenne, D. E.; Braun, D.: Direct detection of antibody concentration and affinity in human serum using microscale thermophoresis. Analytical Chemistry 84 (8), pp. 3523 - 3530 (2012)

Mankan, A. K.; Dau, T.; Jenne, D. E.; Hornung, V.: The NLRP3/ASC/Caspase-1 axis regulates IL-1 ss processing in neutrophils. European Journal of Immunology 42 (3), pp. 710 - 715 (2012)

Mayer, M. C.; Hohlfeld, R.; Meinl, E.: Viability of autoantibody-targets: How to tackle pathogenetic heterogeneity as an obstacle for treatment of multiple sclerosis. JOURNAL OF THE NEUROLOGICAL SCIENCES 319 (1-2), pp. 2 - 7 (2012)

Mayer, M. C.; Meinl, E.: Glycoproteins as targets of autoantibodies in CNS inflammation: MOG and more. Therapeutic Advances in Neurological Disorders 5 (3), pp. 147 - 159 (2012)

Meinl, E.; Meister, G.: MicroRNAs in the CSF Macro-advance in MS? Neurology 79 (22), pp. 2162 - 2163 (2012)

Ng, J. K. M.; Malotka, J.; Kawakami, N.; Derfuss, T.; Khademi, M.; Olsson, T.; Linington, C.; Odaka, M.; Tackenberg, B.; Pruess, H. et al.; Schwab, J. M.; Harms, L.; Harms, H.; Sommer, C.; Rasband, M. N.; Eshed-Eisenbach, Y.; Peles, E.; Hohlfeld, R.; Yuki, N.; Dornmair, K.; Meinl, E.: Neurofascin as a target for autoantibodies in peripheral neuropathies. Neurology 79 (23), pp. 2241 - 2248 (2012)

Odoardi, F.; Sie, C.; Streyl, K.; Ulaganathan, V. K.; Schlaeger, C.; Lodygin, D.; Heckelsmiller, K.; Nietfeld, W.; Ellwart, J.; Klinkert, W. E. F. et al.; Lottaz, C.; Nosov, M.; Brinkmann, V.; Spang, R.; Lehrach, H.; Vingron, M.; Wekerle, H.; Fluegel-Koch, C.; Fluegel, A.: T cells become licensed in the lung to enter the central nervous system. Nature 488 (7413), pp. 675 - 679 (2012)

Perera, N. C.; Jenne, D. E.: Perspectives and potential roles for the newly discovered NSP4 in the immune system. Expert Review of Clinical Immunology 8 (6), pp. 501 - 503 (2012)

Perera, N. C.; Schilling, O.; Kittel, H.; Back, W.; Kremmer, E.; Jenne, D. E.: NSP4, an elastase-related protease in human neutrophils with arginine specificity. Proceedings of the National Academy of Sciences of the United States of America 109 (16), pp. 6229 - 6234 (2012)

Schankin, C. J.; Reifferscheid, A. K.; Krumbholz, M.; Linn, J.; Rachinger, W.; Langer, S.; Sostak, P.; Arzberger, T.; Kretzschmar, H.; Straube, A.: Headache in patients with pituitary adenoma: Clinical and paraclinical findings. Cephalalgia 32 (16), pp. 1198 - 1207 (2012)

Siewert, K.; Malotka, J.; Kawakami, N.; Wekerle, H.; Hohlfeld, R.; Dornmair, K.: Unbiased identification of target antigens of CD8(+) T cells with combinatorial libraries coding for short peptides. Nature Medicine 18 (5), pp. 824 - 828 (2012)

Wekerle, H.; Fluegel, A.; Fugger, L.; Schett, G.; Serreze, D.: Autoimmunity's next top models. Nature Medicine 18 (1), pp. 66 - 70 (2012)

Wekerle, H.; Krishnamoorthy, G.: Brain Autoimmunity: The CD8 Question(s). Immunity 37 (1), pp. 8 - 10 (2012)

Kawakami, N.; Bartholomäus, I.; Pesic, M.; Kyratsous, N. I.: Intravital Imaging of Autoreactive T Cells in Living Animals. In: LABORATORY METHODS IN CELL BIOLOGY: IMAGING, pp. 149 - 168. ELSEVIER ACADEMIC PRESS INC, 525 B STREET, SUITE 1900, SAN DIEGO, CA 92101-4495 USA (2012)

Bhonsle, L.: Characterization of potentially autoaggressive brain infiltrating CD8+ T cells in multiple sclerosis patients. Dissertation, Ludwig-Maximilians-Universität, München (2012)

Bruder, J.: Antigenerkennung bei autoaggressiven Lymphozyten. Dissertation, Julius-Maximilians-Univeristät, Würzburg (2012)

Held, K.: Control of herpes simplex virus type 1 latency in human trigeminal ganglia. Dissertation, Ludwig-Maximilians-Universität, München (2012)

Mues, M.: Imaging Migration and Activation of Lymphocytes: Transgenic Expression of Fluorescent Indicators. Dissertation, Ludwig-Maximilians-Universität, München (2012)

Ng, J. K. M.: Anti-neurofascin antibodies: Assay development and analysis of inflammatory diseases in the peripheral and central nervous system. Dissertation, Ludwig-Maximilians-Universität, München (2012)

Graeber, M. B.; Banati, R. B.; Flügel, A.; Streit, W. J.; Tetzlaff, W.: Courage, luck and patience: In celebration of the 80th birthday of Georg W. Kreutzberg. Acta Neuropathologica 124, pp. 593 - 598 (2012)