Publications

Max Planck Institute for Biological Intelligence

Journal Article (382)

2003

Journal Article

Dalakas, M. C.; Hohlfeld, R.: Polymyositis and dermatomyositis. Lancet 362 (9388), pp. 971 - 982 (2003)

MPG.PuRe

Journal Article

Delarasse, C.; Daubas, P.; Mars, L. T.; Vizler, C.; Litzenburger, T.; Iglesias, A.; Bauer, J.; Della Gaspera, B.; Schubart, A.; Decker, L. et al.; Dimitri, D.; Roussel, G.; Dierich, A.; Amor, S.; Dautigny, A.; Liblau, R.; Pham-Dinh, D.: Myelin/oligodendrocyte glycoprotein-deficient (MOG-deficient) mice reveal lack of immune tolerance to MOG in wild-type mice. Journal of Clinical Investigation 112 (4), pp. 544 - 553 (2003)

MPG.PuRe

Journal Article

Dornmair, K.; Goebels, N.; Weltzien, H. U.; Wekerle, H.; Hohlfeld, R.: T-cell-mediated autoimmunity - Novel techniques to characterize autoreactive T-cell receptors. American Journal of Pathology 163 (4), pp. 1215 - 1226 (2003)

MPG.PuRe

Journal Article

Gold, R.; Linington, C.: Glatiramer acetate treatment in Devic's neuromyelitis optica - Reply. Brain 126, p. E1 - E1 (2003)

MPG.PuRe

Journal Article

Hink-Schauer, C.; Estebanez-Perpina, E.; Kurschus, F. C.; Bode, W.; Jenne, D. E.: Crystal structure of the apoptosis-inducing human granzyme A dimer. Nature Structural Biology 10 (7), pp. 535 - 540 (2003)

MPG.PuRe

Journal Article

Hofbauer, M.; Wiesener, S.; Babbe, H.; Roers, A.; Wekerle, H.; Dornmair, K.; Goebels, N.: Clonal tracking of autoaggressive T cells in polymyositis by combining laser microdissection, single-cell PCR, and CDR3-spectratype analysis. Proceedings of the National Academy of Sciences of the United States of America 100 (7), pp. 4090 - 4095 (2003)

MPG.PuRe

Journal Article

Hohlfeld, R.: Hunting (auto)immune T cells in neuroimmunological diseases. Brain 126, pp. 2 - 4 (2003)

MPG.PuRe

Journal Article

Hohlfeld, R.: The prospects for neuroprotection in MS. International MS Journal 10, pp. 103 - 105 (2003)

MPG.PuRe

Journal Article

Hohlfeld, R.; Dalakas, M.: Basic principles of immunotherapy for neurologic diseases. Seminars in Neurology 23, pp. 121 - 131 (2003)

MPG.PuRe

Journal Article

Jenne, D. E.; Tinschert, S.; Dorschner, M. O.; Hameister, H.; Stephens, K.; Kehrer-Sawatzki, H.: Complete physical map and gene content of the human NFI tumor suppressor region in human and mouse. Genes Chromosomes & Cancer 37 (2), pp. 111 - 120 (2003)

MPG.PuRe

Journal Article

Kehrer-Sawatzki, H.; Tinschert, S.; Jenne, D. E.: Heterogeneity of breakpoints in non-LCR-mediated large constitutional deletions of the 17q11.2 NF1 tumour suppressor region. Journal of Medical Genetics 40 (10), e116 (2003)

MPG.PuRe

Journal Article

Kerschensteiner, M.; Hohlfeld, R.: Neurotrophic factors protect myelin from attack. International MS Journal 10 (1), pp. 2 - 4 (2003)

MPG.PuRe

Journal Article

Kerschensteiner, M.; Stadelmann, C.; Dechant, G.; Wekerle, H.; Hohlfeld, R.: Neurotrophic cross-talk between the nervous and immune systems: Implications for neurological diseases. Annals of Neurology 53 (3), pp. 292 - 304 (2003)

MPG.PuRe

Journal Article

Malatesta, P.; Hack, M. A.; Hartfuss, E.; Kettenmann, H.; Klinkert, W.; Kirchhoff, F.; Götz, M.: Neuronal or glial progeny: Regional differences in radial glia fate. Neuron 37 (5), pp. 751 - 764 (2003)

MPG.PuRe

Journal Article

Pagany, M.; Jagodic, M.; Bourquin, C.; Olsson, T.; Linington, C.: Genetic variation in myelin oligodendrocyte glycoprotein expression and susceptibility to experimental autoimmune encephalomyelitis. Journal of Neuroimmunology 139 (1-2), pp. 1 - 8 (2003)

MPG.PuRe

Journal Article

Pagany, M.; Jagodic, M.; Schubart, A.; Pham-Dinh, D.; Bachelin, C.; van Evercooren, A. B.; Lachapelle, F.; Olsson, T.; Linington, C.: Myelin oligodendrocyte glycoprotein is expressed in the peripheral nervous system of rodents and primates. Neuroscience Letters 350 (3), pp. 165 - 168 (2003)

MPG.PuRe

Journal Article

Petek, E.; Jenne, D. E.; Smolle, J.; Binder, B.; Lasinger, W.; Windpassinger, C.; Wagner, K.; Kroisel, P. M.; Kehrer-Sawatzki, H.: Mitotic recombination mediated by the JJAZF1 (KIAA0160) gene causing somatic mosaicism and a new type of constitutional NF1 microdeletion in two children of a mosaic female with only few manifestations. Journal of Medical Genetics 40 (7), pp. 520 - 525 (2003)

MPG.PuRe

Journal Article

Scheid, R.; Voltz, R.; Guthke, T.; Bauer, J.; Sammler, D.; von Cramon, D. Y.: Neuropsychiatric findings in anti-Ma2 positive paraneoplastic limbic encephalitis. Neurology 61 (8), pp. 1159 - 1161 (2003)

MPG.PuRe

Journal Article

Theil, D.; Derfuss, T.; Paripovic, I.; Herberger, S.; Meinl, E.; Schueler, O.; Strupp, M.; Arbusow, V.; Brandt, T.: Latent herpesvirus infection in human trigeminal ganglia causes chronic immune response. American Journal of Pathology 163 (6), pp. 2179 - 2184 (2003)

MPG.PuRe

Journal Article

Voltz, R.; Albrich, W.; Hohlfeld, R.; Nagel, D.; Wick, M.; Kirchner, T.; Sommer, N.; Illa, I.; Kaminski, H.; Schumm, F.: Anti-titin antibodies are not associatd with a specific thymoma histology. Journal of Neurology, Neurosurgery and Psychiatry 74, p. 282 - 282 (2003)

MPG.PuRe

Journal Article

Wekerle, H.; Hohlfeld, R.: Molecular mimicry in multiple sclerosis. New England Journal of Medicine 349 (2), pp. 185 - 186 (2003)

MPG.PuRe

Journal Article

Wiendl, H.; Mitsdörfer, M.; Hofmeister, V.; Wischhusen, J.; Weiss, E. H.; Dichgans, J.; Lochmüller, H.; Hohlfeld, R.; Melms, A.; Weller, M.: The non-classical MHC molecule HLA-G protects human muscle cells from immune-mediated lysis: Implications for myoblast transplnatation and gene therapy. Brain 126, pp. 176 - 185 (2003)

MPG.PuRe

Journal Article

Zocher, M.; Baeuerle, P. A.; Dreier, T.; Iglesias, A.: Specific depletion of autoreactive B lymphocytes by a recombinant fusion protein in vitro and in vivo. International Immunology 15 (7), pp. 789 - 796 (2003)

MPG.PuRe

2002

Journal Article

Abdul-Majid, K. B.; Stefferl, A.; Bourquin, C.; Lassmann, H.; Linington, C.; Olsson, T.; Kleinau, S.; Harris, R. A.: Fc receptors are critical for autoimmune inflammatory damage to the central nervous system in experimental autoimmune encephalomyelitis. Scandinavian Journal of Immunology 55 (1), pp. 70 - 81 (2002)

MPG.PuRe

Journal Article

Andersson, M.; Yu, M.; Soderstrom, M.; Weerth, S.; Baig, S.; Linington, C.; Solders, G.; Link, H.: Multiple MAG peptides are recognized by circulating T and B lymphocytes in polyneuropathy and multiple sclerosis. European Journal of Neurology 9 (3), pp. 243 - 251 (2002)

MPG.PuRe

Journal Article

Bauer, J.; Bradl, M.; Klein, M.; Leisser, M.; Deckwerth, T. L.; Wekerle, H.; Lassmann, H.: Endoplasmic reticulum stress in PLP-overexpressing transgenic rats: Gray matter oligodendrocytes are more vulnerable than white matter oligodendrocytes. Journal of Neuropathology and Experimental Neurology 61 (1), pp. 12 - 22 (2002)

MPG.PuRe

Journal Article

Berninger, B.; Bi, G. Q.: Synaptic modification in neural circuits: A timely action. Bioessays 24 (3), pp. 212 - 222 (2002)

MPG.PuRe

Journal Article

Bradl, M.; Flügel, A.: The role of T cells in brain pathology. Curr Top Microbiol Immunol. 265, pp. 141 - 162 (2002)

MPG.PuRe

Journal Article

Burger, B.; Uhlhaas, S.; Mangold, E.; Propping, P.; Friedl, W.; Jenne, D. E.; Dockter, G.; Back, W.: Novel de novo mutation of MADH4/SMAD4 in a patient with juvenile polyposis. American Journal of Medical Genetics 110 (3), pp. 289 - 291 (2002)

MPG.PuRe

Journal Article

Campbell, P. K.; Waymire, K. G.; Heier, R. L.; Sharer, C.; Day, D. E.; Reimann, H.; Jaje, J. M.; Friedrich, G. A.; Burmeister, M.; Bartness, T. J. et al.; Russell, L. D.; Young, L. J.; Zimmer, M.; Jenne, D. E.; MacGregor, G. R.: Mutation of a novel gene results in abnormal development of spermatid flagella, loss of intermale aggression and reduced body fat in mice. Genetics 162 (1), pp. 307 - 320 (2002)

MPG.PuRe

Journal Article

Clanet, M.; Radue, E. W.; Kappos, L.; Hartung, H. P.; Hohlfeld, R.; Sandberg-Wollheim, M.; Kooijmans-Coutinho, M. F.; Tsao, E. C.; Sandrock, A. W.; European IFNß-1a (Avonex) Dose-Comparison Study Investigators: A randomised, double-blind, dose-comparison study of weekly interferon ß-1a in relapsing MS. Neurology 59 (10), pp. 1507 - 1517 (2002)

MPG.PuRe

Journal Article

Farina, C.; Vargas-Leal, V.; Heydari, N.; Kümpfel, T.; Meinl, E.; Hohlfeld, R.: Treatment with glatiramer acetate induces specific IgG4 antibodies in multiple sclerosis patients. Journal of Neuroimmunology 123 (1-2), pp. 188 - 192 (2002)

MPG.PuRe

Journal Article

Farina, C.; Wagenpfeil, S.; Hohlfeld, R.: Immunological assay for assessing the efficacy of glatiramer acetate (Copaxone) in multiple sclerosis - A pilot study. Journal of Neurology 249 (11), pp. 1587 - 1592 (2002)

MPG.PuRe

Journal Article

Gold, R.; Linington, C.: Devic's disease: Bridging the gap between laboratory and clinic. Brain 125, pp. 1425 - 1427 (2002)

MPG.PuRe

Journal Article

Hammer, M. H.; Schroder, G.; Risch, K.; Flügel, A.; Volk, H. D.; Lehmann, M.; Ritter, T.: Antigen-dependent transgene expression in kidney transplantation: A novel approach using gene-engineered T lymphocytes. Journal of the American Society of Nephrology 13 (2), pp. 511 - 518 (2002)

MPG.PuRe

Journal Article

Hink-Schauer, C.; Estebanez-Perpina, E.; Wilharm, E.; Fuentes-Prior, P.; Klinkert, W. E. F.; Bode, W.; Jenne, D. E.: The 2.2-angstrom crystal structure of human pro-granzyme K reveals a rigid zymogen with unusual features. Journal of Biological Chemistry 277 (52), pp. 50923 - 50933 (2002)

MPG.PuRe

Journal Article

Hohlfeld, R.: Myelin failure in multiple sclerosis: Breaking the spell of Notch. Nature Medicine 8 (10), pp. 1075 - 1076 (2002)

MPG.PuRe

Journal Article

Hohlfeld, R.: How promising is hematopoetic stem cell transplantation in multiple sclerosis? J Neurol. 249, pp. 1147 - 1149 (2002)

MPG.PuRe

Journal Article

Jishage, K.; Nezu, J.; Kawase, Y.; Iwata, T.; Watanabe, M.; Miyoshi, A.; Ose, A.; Habu, K.; Kake, T.; Kamada, N. et al.; Ueda, O.; Kinoshita, M.; Jenne, D. E.; Shimane, M.; Suzuki, H.: Role of Lkb1, the causative gene of Peutz-Jegher's syndrome, in embryogenesis and polyposis. Proceedings of the National Academy of Sciences of the United States of America 99 (13), pp. 8903 - 8908 (2002)

MPG.PuRe

Journal Article

Kirchhoff, S.; Sebens, T.; Baumann, S.; Krueger, A.; Zawatzky, R.; Min, L. W.; Meinl, E.; Neipel, F.; Fleckenstein, B.; Krammer, P. H.: Viral IFN-regulatory factors inhibit activation-induced cell death via two positive regulatory IFN-Regulatory factor 1- dependent domains in the CD95 ligand promoter. Journal of Immunology 168 (3), pp. 1226 - 1234 (2002)

MPG.PuRe

Journal Article

Meinl, E.; Hohlfeld, R.: Immunopathogenesis of multiple sclerosis: MBP and beyond. Clinical and Experimental Immunology 128 (3), pp. 395 - 397 (2002)

MPG.PuRe

Journal Article

Neumann, H.; Schweigreiter, R.; Yamashita, T.; Rosenkranz, K.; Wekerle, H.; Barde, Y. A.: Tumor necrosis factor inhibits neurite outgrowth and branching of hippocampal neurons by a Rho-dependent mechanism. The Journal of Neuroscience 22 (3), pp. 854 - 862 (2002)

MPG.PuRe

Journal Article

Popovic, N.; Schubart, A.; Goetz, B. D.; Zhang, S. C.; Linington, C.; Duncan, I. D.: Inhibition of autoimmune encephalomyelitis by a tetracycline. Annals of Neurology 51 (2), pp. 215 - 223 (2002)

MPG.PuRe

Journal Article

Scolding, N. J.; Wilson, H.; Hohlfeld, R.; Polman, C.; Leite, I.; Gilhus, N.; The EFNS Crebral Vasculitis Task Force: The recognition, diagnosis and management of cerebral vasculitis: A European survey. European Journal of Neurology 9 (4), pp. 343 - 347 (2002)

MPG.PuRe

Journal Article

Stadelmann, C.; Kerschensteiner, M.; Misgeld, T.; Bruck, W.; Hohlfeld, R.; Lassmann, H.: BDNF and gp145trkB in multiple sclerosis brain lesions: Neuroprotective interactions between immune and neuronal cells? Brain 125, pp. 75 - 85 (2002)

MPG.PuRe

Journal Article

Storch, M. K.; Weissert, R.; Stefferl, A.; Birnbacher, R.; Wallstrom, E.; Dahlman, I.; Ostensson, C. G.; Linington, C.; Olsson, T.; Lassmann, H.: MHC gene related effects on microglia and macrophages in experimental autoimmune encephalomyelitis determine the extent of axonal injury. Brain Pathology 12 (3), pp. 287 - 299 (2002)

MPG.PuRe

Journal Article

Weidinger, G.: Measles virus-specific T-cell immunity in rodent models. Viral Immunology 15 (3), pp. 429 - 434 (2002)

MPG.PuRe

Journal Article

Wekerle, H.: Immune protection of the brain - Efficient and delicate. The Journal of Infectious Diseases 186 (Suppl. 2), pp. S140 - S144 (2002)

MPG.PuRe

Journal Article

Wekerle, H.: Tackling multiple sclerosis. Nature 420 (6911), pp. 39 - 40 (2002)

MPG.PuRe

Journal Article

Wiendl, H.; Hohlfeld, R.: Therapeutic approaches in multiple sclerosis - Lessons from failed and interrupted treatment trials. Biodrugs 16 (3), pp. 183 - 200 (2002)

MPG.PuRe