Publications

Max Planck Institute for Biological Intelligence

Journal Article (382)

2005

Journal Article

Kawakami, N.; Nägerl, U. V.; Odoardi, F.; Bonhoeffer, T.; Wekerle, H.; Flügel, A.: Live imaging of effector cell trafficking and autoantigen recognition within the unfolding autoimmune encephalomyelitis lesion. Journal of Experimental Medicine 201 (11), pp. 1805 - 1814 (2005)

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Kawakami, N.; Odoardi, F.; Ziemssen, T.; Bradl, M.; Ritter, T.; Neuhaus, O.; Lassmann, H.; Wekerle, H.; Flügel, A.: Autoimmune CD4(+) T cell memory: Lifelong persistence of encephalitogenic T cell clones in healthy immune repertoires. Journal of Immunology 175 (1), pp. 69 - 81 (2005)

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Krumbholz, M.; Specks, U.; Wick, M.; Kalled, S. L.; Jenne, D. E.; Meinl, E.: BAFF is elevated in serum of patients with Wegener's granulomatosis. Journal of Autoimmunity 25 (4), pp. 298 - 302 (2005)

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Krumbholz, M.; Theil, D.; Derfuss, T.; Rosenwald, A.; Schrader, F.; Monoranu, C. M.; Kalled, S. L.; Hess, D. M.; Serafini, B.; Aloisi, F. et al.; Wekerle, H.; Hohlfeld, R.; Meinl, E.: BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma. Journal of Experimental Medicine 201 (2), pp. 195 - 200 (2005)

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Kurschus, F. C.; Bruno, R.; Fellows, E.; Falk, C. S.; Jenne, D. E.: Membrane receptors are not required to deliver granzyme B during killer cell attack. Blood 105 (5), pp. 2049 - 2058 (2005)

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Rauschka, H.; Farina, C.; Sator, P.; Gudek, S.; Breier, F.; Schmidbauer, M.: Severe anaphylactic reaction to glatiramer acetate with specific IgE. Neurology 64 (8), pp. 1481 - 1482 (2005)

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Schmid, C.; Diem, H.; Herrman, K.; Voltz, R.; Ott, G.; Hallek, M.: Unusual sites of malignancies: CASE 2. Central neurogenic hyperventilation as a complication of Richter's syndrome. Journal of Clinical Oncology 23 (9), pp. 2096 - 2098 (2005)

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Schuller, M.; Jenne, D. E.; Voltz, R.: The human PNMA family: Novel neuronal proteins implicated in paraneoplastic neurological disease. Journal of Neuroimmunology 169 (1-2), pp. 172 - 176 (2005)

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Spiegel, M.; Oexle, K.; Horn, D.; Windt, E.; Buske, A.; Albrecht, B.; Prott, E. C.; Seemanova, E.; Seidel, J.; Rosenbaum, T. et al.; Jenne, D. E.; Kehrer-Sawatzki, H. K.; Tinschert, S.: Childhood overgrowth in patients with common NF1 microdeletions. European Journal of Human Genetics 13 (7), pp. 883 - 888 (2005)

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Theil, D.; Farina, C.; Meinl, E.: Differential expression of CD150 (SLAM) on monocytes and macrophages in chronic inflammatory contexts: Abundant in Crohn's disease, but not in multiple sclerosis. Journal of Clinical Pathology 58 (1), pp. 110 - 111 (2005)

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Vargas-Leal, V.; Bruno, R.; Derfuss, T.; Krumbholz, M.; Hohlfeld, R.; Meinl, E.: Expression and function of glial cell line-derived neurotrophic factor (GDNF) family ligands and their receptors on human immune cells. Journal of Immunology 175 (4), pp. 2301 - 2308 (2005)

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Wekerle, H.: Immune pathogenesis of multiple sclerosis. Neurological Sciences 26 (1), pp. S1 - S2 (2005)

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Wekerle, H.: Planting and pruning in the brain: MHC antigens involved in synaptic plasticity? Proceedings of the National Academy of Sciences of the United States of America 102 (1), pp. 3 - 4 (2005)

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Wiendl, H.; Hohlfeld, R.; Kieseier, B. C.: Immunobiology of muscle: Advances in understanding an immunological microenvironment. Trends in Immunology 26, pp. 373 - 380 (2005)

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Wiesner, O.; Litwiller, R. D.; Hummel, A. M.; Viss, M. A.; McDonald, C. J.; Jenne, D. E.; Fass, D. N.; Specks, U.: Differences between human proteinase 3 and neutrophil elastase and their murine homologues are relevant for murine model experiments. FEBS Letters 579 (24), pp. 5305 - 5312 (2005)

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Zagrebelsky, M.; Holz, A.; Dechant, G.; Barde, Y. A.; Bonhoeffer, T.; Korte, M.: The p75 neurotrophin receptor negatively modulates dendrite complexity and spine density in hippocampal neurons. The Journal of Neuroscience 25 (43), pp. 9989 - 9999 (2005)

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Ziemssen, T.; Kümpfel, T.; Schneider, H.; Klinkert, W. E. F.; Neuhaus, O.; Hohlfeld, R.: Secretion of brain-derived neurotrophic factor by glatiramer acetate-reactive T-helper cell lines: Implications for multiple sclerosis therapy. Journal of the Neurological Sciences 233 (1-2), pp. 109 - 112 (2005)

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2004

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Aboul-Enein, F.; Bauer, J.; Klein, M.; Schubart, A.; Flügel, A.; Ritter, T.; Kawakami, N.; Siedler, F.; Linington, C.; Wekerle, H. et al.; Lassmann, H.; Bradl, M.: Selective and antigen-dependent effects of myelin degeneration on central nervous system inflammation. Journal of Neuropathology and Experimental Neurology 63 (12), pp. 1284 - 1296 (2004)

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Clanet, M.; Kappos, L.; Hartung, H. P.; Hohlfeld, R.; The European IFNβ-1a Dose Comparison Study Investigators: Interferon β-1a in relapsing multiple sclerosis: Four-year extension of the European IFNβ-1a Dose Comparison Study. Multiple Sclerosis Journal 10, pp. 139 - 144 (2004)

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Dornmair, K.; Schneider, C. K.; Malotka, J.; Dechant, G.; Wiendl, H.; Hohlfeld, R.: Antigen recognition properties of a V gamma LW delta 2-T-cell receptor from a rare variant of polymyositis. Journal of Neuroimmunology 152 (1-2), pp. 168 - 175 (2004)

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Farina, C.; Theil, D.; Semlinger, B.; Hohlfeld, R.; Meinl, E.: Distinct responses of monocytes to Toll-like receptor ligands and inflammatory cytokines. International Immunology 16 (6), pp. 799 - 809 (2004)

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Graus, F.; Delattre, J.Y.; Antoine, J.C.; Dalmau, J.; Giometto, B.; Grisold, W.; Honnorat, J.; Sillevis Smitt, P.; Vedeler, C.; Verschuuren, J.J.G.M. et al.; Vincent, A.; Voltz, R.: For the Paraneoplastic Neurological Syndrome Euronetwork. Recommended diagnostic criteria for paraneoplastic neurological syndromes. Journal of Neurology, Neurosurgery and Psychiatry 75 (8), pp. 1135 - 1140 (2004)

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Guggenmos, J.; Schubart, A. S.; Ogg, S.; Andersson, M.; Olsson, T.; Mather, I. H.; Linington, C.: Antibody cross-reactivity between myelin oligodendrocyte glycoprotein and the milk protein butyrophilin in multiple sclerosis. Journal of Immunology 172 (1), pp. 661 - 668 (2004)

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Hohlfeld, R.: Immunologic factors in primary progressive multiple sclerosis. Multiple Sclerosis 10, pp. 16 - 22 (2004)

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Hohlfeld, R.; Wekerle, H.: Autoimmune concepts of multiple sclerosis as a basis for selective immunotherapy: From pipe dreams to (therapeutic) pipelines. Proceedings of the National Academy of Sciences of the United States of America 101 (Suppl. Suppl. 2), pp. 14599 - 14606 (2004)

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Karrasch, T.; Weil, M.; Voltz, R.; Schulz, C.; Audebert, F.; Woenckhaus, M.; Hofstädter, F.; Bogdahn, U.; Scholmerich, J.; Schäffler, A. et al.; Steinbrecher, A.: "Fußkribbeln", Vergesslichkeit und progrediente Wesensveränderung bei einer 63-jährigen Patientin. Internist 45 (3), pp. 341 - 346 (2004)

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Kawakami, N.; Lassmann, S.; Li, Z. X.; Odoardi, F.; Ritter, T.; Ziemssen, T.; Klinkert, W. E. F.; Ellwart, J. W.; Bradl, M.; Krivacic, K. et al.; Lassmann, H.; Ransohoff, R. M.; Volk, H. D.; Wekerle, H.; Linington, C.; Flügel, A.: The activation status of neuroantigen-specific T cells in the target organ determines the clinical outcome of autoimmune encephalomyelitis. Journal of Experimental Medicine 199 (2), pp. 185 - 197 (2004)

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Kawakami, N.; Nägerl, U. V.; Wekerle, H.; Flügel, A.: Live-imaging of encephalitogenic T lymphocytes in the living target tissue. Journal of Neuroimmunology 154 (1-2 Sp. Iss. Sp. Iss. SI), p. 224 - 224 (2004)

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Kehrer-Sawatzki, H.; Kluwe, L.; Sandig, C.; Kohn, M.; Wimmer, K.; Krammer, U.; Peyrl, A.; Jenne, D. E.; Hansmann, I.; Mautner, V. F.: High frequency of mosaicism among patients with neurofibromatosis type 1 (NF1) with microdeletions caused by somatic recombination of the JJAZ1 gene. American Journal of Human Genetics 75 (3), pp. 410 - 423 (2004)

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Kurschus, F. C.; Kleinschmidt, M.; Fellows, E.; Dornmair, K.; Rudolph, R.; Lilie, H.; Jenne, D. E.: Killing of target cells by redirected granzyme B in the absence of perforin. FEBS Letters 562 (1-3), pp. 87 - 92 (2004)

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Liliensiek, B.; Weigand, M. A.; Bierhaus, A.; Nicklas, W.; Kasper, M.; Hofer, S.; Plachky, J.; Grone, H. J.; Kurschus, F. C.; Schmidt, A. M. et al.; Yan, S. D.; Martin, E.; Schleicher, E.; Stern, D. M.; Hammerling, G. G.; Nawroth, P. P.; Arnold, B.: Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response. The Journal of Clinical Investigation 113 (11), pp. 1641 - 1650 (2004)

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Linke, R.; Schröder, M.; Helmberger, T.; Voltz, R.: Antibody-positive paraneoplastic neuroligical syndromes: The value of CT and FDG-PET imaging for tumor diagnosis. Neurology 63 (2), pp. 282 - 286 (2004)

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Mead, R. J.; Neal, J. W.; Griffiths, M. R.; Linington, C.; Botto, M.; Lassmann, H.; Morgan, B. P.: Deficiency of the complement regulator CD59a enhances disease severity, demyelination and axonal injury in murine acute experimental allergic encephalomyelitis. Laboratory Investigation 84 (1), pp. 21 - 28 (2004)

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Meinl, E.; Voltz, R.: Biomarker in der Therapie der Multiplen Sklerose: Läßt sich der Erfolg bald vorhersagen? MMW-Fortschr. Med. Sonderheft 2, p. 517 - 517 (2004)

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Neuhaus, O.; Kieseier, B. C.; Klimke, A.; Gaebel, W.; Hohlfeld, R.; Hartung, H. P.: Cannabinoids in multiple sclerosis. Opportunity or threat? Nervenarzt 75 (10), pp. 1022 - 1026 (2004)

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Pellkofer, H.; Schubart, A. S.; Hoftberger, R.; Schutze, N.; Pagany, M.; Schuller, M.; Lassmann, H.; Hohlfeld, R.; Voltz, R.; Linington, C.: Modelling paraneoplastic CNS disease: T-cells specific for the onconeuronal antigen PNMA1 mediate autoimmune encephalomyelitis in the rat. Brain 127, pp. 1822 - 1830 (2004)

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Pfister, H.; Ollert, M.; Fröhlich, L. O.; Quintanilla-Fend, L.; Colby, T. V.; Specks, U.; Jenne, D. E.: Autoantibodies against the murine homolog of Wegener’s autoantigen (proteinase 3) are pathogenic in vivo. Blood 104, pp. 1411 - 1418 (2004)

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Pfister, H.; Ollert, M.; Fröhlich, L. F.; Quintanilla-Martinez, L.; Colby, T. V.; Specks, U.; Jenne, D. E.: Antineutrophil cytoplasmic autoantibodies against the murine homolog of proteinase 3 (Wegener autoantigen) are pathogenic in vivo. Blood 104 (5), pp. 1411 - 1418 (2004)

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Scheid, R.; Lincke, T.; Voltz, R.; von Cramon, D. Y.; Sabri, O.: Serial 18F-fluoro-2deoxy-D-glucose positron emission tomography and magnetic resonance imaging of paraneoplastic limbic encephalitis. Archives of Neurology 61 (11), pp. 1785 - 1789 (2004)

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Skulina, C.; Schmidt, S.; Dornmair, K.; Babbe, H.; Roers, A.; Rajewsky, K.; Wekerle, H.; Hohlfeld, R.; Goebels, N.: Multiple sclerosis: Brain-infiltrating CD8(+) T cells persist as clonal expansions in the cerebrospinal fluid and blood. Proceedings of the National Academy of Sciences of the United States of America 101 (8), pp. 2428 - 2433 (2004)

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Thurau, S. R.; Mempel, T. R.; Flügel, A.; Diedrichs-Moehring, M.; Krombach, F.; Kawakami, N.; Wildner, G.: The fate of autoreactive, GFP(+) T cells in rat models of uveitis analyzed by intravital fluorescence microscopy and FACS. International Immunology 16 (11), pp. 1573 - 1582 (2004)

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Voltz, R.; Starck, M.; Zingler, V.; Strupp, M.; Kolb, H.J.: Mitoxantrone therapy in multiple sclerosis and acute leukaemia: A case report out ot 644 treated patients. Multiple Sclerosis 10, pp. 472 - 474 (2004)

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Weber, M. S.; Starck, M.; Wagenpfeil, S.; Meinl, E.; Hohlfeld, R.; Farina, C.: Multiple sclerosis: Glatiramer acetate inhibits monocyte reactivity in vitro and in vivo. Brain 127, pp. 1370 - 1378 (2004)

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Wiesner, O.; Russell, K. A.; Lee, A. S.; Jenne, D. E.; Trimarchi, M.; Gregorini, G.; Specks, U.: Antineutrophil cytoplasmic antibodies reacting with human neutrophil elastase as a diagnostic marker for cocaine-induced midline destructive lesions but not autoimmune vasculitis. Arthritis and Rheumatism 50 (9), pp. 2954 - 2965 (2004)

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2003

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Arbour, N.; Holz, A.; Sipe, N.C.; Naniche, D.; Romine, J.S.; Zyroff, J.; Oldstone, M.B.A.: A new approach for evaluating antigen-specific T cell responses to myelin antigens during the course of multiple sclerosis. Journal of Neuroimmunology 137, pp. 197 - 209 (2003)

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Bausewein, C.; Hau, P.; Dudel, C.; Hartenstein, R.; Bogdahn, U.; Borasio, G.D.; Voltz, R.: How do patients with brain tumors die? Palliative Medicine 17 (6), pp. 558 - 559 (2003)

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Bourquin, C.; Schubart, A.; Tobollik, S.; Mather, I.; Ogg, S.; Liblau, R.; Linington, C.: Selective unresponsiveness to conformational B cell epitopes of the myelin oligodendrocyte glycoprotein in H-2(b) mice. Journal of Immunology 171 (1), pp. 455 - 461 (2003)

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Bradl, M.; Hohlfeld, R.: Neuroscience for Neurologists: Molecular pathogenesis of neuroinflammation. Journal of Neurology, Neurosurgery and Psychiatry 74, pp. 1364 - 1370 (2003)

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Breithaupt, C.; Schubart, A.; Zander, H.; Skerra, A.; Huber, R.; Linington, C.; Jacob, U.: Structural insights into the antigenicity of myelin oligodendrocyte glycoprotein. Proceedings of the National Academy of Sciences of the United States of America 100 (16), pp. 9446 - 9451 (2003)

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Dalakas, M. C.; Hohlfeld, R.: Diagnostic criteria for polymyositis and dermatomyositis - Reply. Lancet 362 (9397), p. 1763 - 1763 (2003)

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